Triamterene 37.5mg, hydrochlorothiazide 25mg; caps. Triamterene exerts its diuretic effect on the distal renal tubule to inhibit the reabsorption of sodium in exchange for potassium and hydrogen ions.

Although diuresis and natriuresis did not result from hydrochlorothiazide or from triamterene these agents differed in their effects on potassium excretion. Hydrochlorothiazide induced significant ...