Four studies examine this question, delving deeply into the role of the transcription factor Foxp3 in governing Treg differentiation and function. Tregs play essential roles in immune homeostasis ...

Stationed within the meninges, squads of immune cells lie in wait, ready to unleash an inflammatory assault within the brain if needed. Holding these trigger-happy troops back during peacetime falls ...

Quell has developed a platform that works by ensuring the sustained expression of forkhead box P3 (FOXP3) in Treg cells. This protein is a crucial regulator of Treg cell gene expression and is ...

RA drives the development of Tregs by activating Forkhead box P3 (Foxp3), the master transcription factor for Treg differentiation. Read the full story here.