肿瘤浸润调节性T细胞(Tumor-infiltrating regulatory T cells,TI-Treg cells)是肿瘤微环境中抑制抗肿瘤免疫并促进肿瘤进展的关键免疫细胞。尽管已有多种疗法旨在靶向TI-Treg细胞,然而大多数治疗效果不佳 ...
Four studies examine this question, delving deeply into the role of the transcription factor Foxp3 in governing Treg differentiation and function. Tregs play essential roles in immune homeostasis ...
Quell has developed a platform that works by ensuring the sustained expression of forkhead box P3 (FOXP3) in Treg cells. This ...