The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion. While healthy ...

Insights into the structures could lead to improved treatment strategies for transthyretin amyloidosis, a progressive, fatal disease in men.

BridgeBio could be an acquisition target, but current financial challenges and competition suggest a "Hold" rating until ...

Scripps Research scientists discovered that some sections of the hormone-carrying molecule transthyretin (left) are in constant motion (right), which may explain why the protein can misfold and ...

Scripps Research scientists discovered that some sections of the hormone-carrying molecule transthyretin (left) are in constant motion (right), which may explain why the protein can misfold and ...

In this essay, we will explore the symptoms of ATTR-CM and the five treatment options available for the heart condition.

which causes the liver to produce abnormal transthyretin protein. Abnormal transthyretin can clump and form deposits in the tissues of the body (amyloidosis) which can disrupt the structure and ...

NI006 is an antibody that binds to the misfolded forms of the transthyretin protein that form the fibrils, and cause them to be cleared away by immune cells like macrophages. Tafamidis is thought ...

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