Post-translational modifications are as, or even more, important than transcriptional regulation to finely tune circadian rhythms. Oscillations in period (PER) and cryptochrome (CRY) protein ...

Similarities to the post-translational modification phosphorylation suggest that AMPylation may be an important regulatory mechanism. Post-translational modifications are key steps in the ...

The research could contribute to the development of more effective anti-aging treatments in the future. The body's aging ...

These studies revealed structural determinants for recognition of consensus SUMO modification sequences found within SUMO conjugated proteins. Reconstituting SUMO conjugation in vitro revealed ...

A major, but not exclusive focus of our lab is the analysis of histones, their variants, post-translational modifications and proteoforms. Histones are essential regulators of the human genome and ...

Use precise geolocation data and actively scan device characteristics for identification. This is done to store and access ...

Many membrane proteins also require post-translational modifications, such as glycosylation, to function properly. Current technologies for studying membrane proteins either involve expression in ...

As a shared facility of the Bindley Bioscience Center (BBC) in Discovery Park of Purdue University, the facility enables both targeted and global analysis of proteins, their post-translational ...