Developmental biologists discover how a critical protein shapes gallbladder formation
The lab of Dr. Mark Magnuson, Louise B. McGavock Professor and professor of molecular physiology and biophysics at Vanderbilt ...
The Scientist1y
“Cryptic Transcription”: How Aging Cells Express Fragments of Genes
The team turned to a precision nuclear run-on sequencing technique called PRO-cap, which allowed them to determine the start site of transcription in DNA by sequencing the corresponding first few ...
Nature4y
DNA Transcription
Most pol II genes have a TATA box (consensus sequence TATTAA) 25 to 35 bases upstream of the initiation site, which affects the transcription rate and determines location of the start site.
Nature7y
transcription factor / transcription factors
Some transcription factors bind to a DNA promoter sequence near the transcription start site and help form the transcription initiation complex. Other transcription factors bind to regulatory ...