Mediator is a common target of DNA-binding transcription factors (TFs) and also interacts with various Pre-Initiation Complex (PIC) factors. The PIC consists of TFIIA, TFIIB, TFIID, TFIIE, TFIIF, ...

Transcription factors are proteins involved in the process of converting, or transcribing, DNA into RNA. Transcription factors include a wide number of proteins, excluding RNA polymerase, that ...

New research has uncovered more about the complexity of human gene regulation by identifying certain sequences of proteins ...

Research into transcription factors deepen understanding of the 'language' of the genome, offering insights into human development.

A block to more potent and specific release of HIV from latency has been identified as a subunit of the Integrator complex, which may aid strategies for HIV cure.

Transcription factors bind to the TATA box and initiate the formation of the RNA polymerase transcription complex, which promotes transcription.

This complex liver disorder ranges from simple ... The latest insights into transcription factors provide a deeper understanding of the disease's progression and potential therapeutic interventions.