Telithromycin was the first ketolide approved for use in the U.S. More than 30% of this agent is metabolized in the liver. Now, three cases of severe hepatotoxicity associated with telithromycin ...

Telithromycin is effective for the treatment of common respiratory pathogens and also retains activity against penicillin- and erythromycin-resistant isolates. Telithromycin should be reserved for ...