Telithromycin was the first ketolide approved for use in the U.S. More than 30% of this agent is metabolized in the liver. Now, three cases of severe hepatotoxicity associated with telithromycin ...

Telithromycin (Ketek AE) is a ketolide antibiotic which blocks bacterial protein synthesis. Structural derivatives of macrolide antibiotics, ketolides are erythromycin-type drugs. Telithro mycin ...