Cylindromatosis is a rare tumour of the skin appendages, and is caused by mutation of the tumour suppressor CYLD; however, the function of this gene has only recently been determined. Three papers ...

Dr. Ma adds, "Our results show that BB1 prevented the TNF-α increase in intestinal tight junction permeability via a toll-like receptor (TLR)-2 signal transduction pathway inhibition of NF-kB p50 ...