来自MSN8 个月
Review highlights the interplay of TGF-β and HIPPO pathways in liver regeneration and disease
The TGF-β pathway can inhibit YAP/TAZ activity, crucial components of the HIPPO pathway, thus modulating cell proliferation and apoptosis. This interaction is vital for restoring liver function ...
Nature3 个月
Integrating Myc and TGF-β signalling in cell-cycle control
Expression of the cell cycle inhibitor p15 INK4b is suppressed by the Myc oncoprotein and induced by transforming growth factor-β (TGF-β). The transcription factor Miz-1 activates the Ink4b ...