More information: Yu Hou et al, Neuropeptide signalling orchestrates T cell differentiation, Nature (2024). DOI: ...

Understanding how cells transform into specialized types during human development is a central challenge in biology. This ...

Philip M and Schietinger A. CD8 T cell differentiation and dysfunction in cancer. Nature Reviews Immunology. 2022 Apr;22(4):209-223. TOX is a critical regulator of tumour-specific T cell ...

Plant cells are also able to become longer as they grow. This process is called cell elongation and occurs throughout the plant, not just in the meristems. Cell elongation does not occur in animals.

Scientists from our program have played a central role in the development of several types of immunotherapy that are currently transforming cancer care, including checkpoint blockade and CAR T cell ...

Nutrient access and metabolism regulate lymphocyte function, crucial in demanding environments like tumors. Dr. Delgoffe explores T cell metabolic defects in solid tumors and unveils strategies to ...