We discovered the function of the thymus and made key findings on the function of the two main subsets of lymphocytes, T cells and B cells. This was the fundamental basis for modern immunology.
Tumor-infiltrating lymphocyte functions, metabolic profiles ... could jump from cancer cells into T-cells. These transferred mitochondria carried functional errors in their DNA that interfered ...
The progressive autoimmune destruction of pancreatic β cells characteristic of T1DM is widely believed to involve T lymphocytes ... of B lymphocytes can preserve β-cell function in patients ...
Autoimmune thyroid disease (AITD) causes cellular damage and alters thyroid gland function by humoral and cell-mediated mechanisms. Cellular damage occurs when sensitized T-lymphocytes and/or ...
However, their effectiveness has plateaued due to therapeutic resistance that renders tumor-infiltrating lymphocytes ... how HIF1α in T cells is key for induction of interferon gamma, or IFN ...
The cell type, CD8 + cytotoxic T lymphocytes that express a transcription factor called ZNF683/Hobit at high levels, appear to coordinate with other immune cells to expand and attack leukemia cells.
Lymphocytes, a type of immune cell, are essential in combating infections within the body. The adaptive immune system primarily consists of T cells and B cells, each serving specific functions in ...
It is the first comprehensive cellular analysis of ALS, carried out using single-cell RNA sequencing in 14 patients and 14 ...
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