Bifloranes, also known as serrulatanes, feature a distinct 6,6-bicyclic framework and a prenyl side chain, showcasing a wide ...

TVB-3567 is the Company’s second fatty acid synthase (FASN) inhibitor First-in-human Phase 1 trial initiation planned in 2025 ...

A recent study reveals how the expansion and functional divergence of terpene synthase genes (TPSs) in flowering plants ...

Mineralys Therapeutics enjoyed a big stock bump after its aldosterone synthase inhibitor chalked up wins in two types of ...

Topline data were announced from a phase 3 trial investigating lorundrostat for the treatment of uncontrolled hypertension or resistant hypertension.

Sagimet Biosciences Inc. has obtained IND clearance from the FDA for TVB-3567 (ASC-60), a selective small-molecule fatty acid ...

Crystal structures of human endothelial nitric oxide synthase (eNOS) and human inducible NOS (iNOS) catalytic domains were solved in complex with the arginine substrate and an inhibitor S ...

Their study has also identified that this process is mediated by the induction of hyaluronan synthase 3 (HAS3) expression. In Japan, cadmium is well known as the causative agent of Itai-itai ...

Positive top-line data from phase II and III studies of lorundrostat for treating uncontrolled or resistant hypertension ...