Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia characterized by the accumulation of promyelocytes in the bone marrow and blood. Recent research has focused on improving ...

was diagnosed with leukemia after doctors dismissed his symptoms as tonsillitis or a "bug going around" The boy had a sore throat, cough, and swollen glands — but it was the bruising on his back ...

The research, published in the July issue of the journal Cancer Cell, published by Cell Press, illuminates specific mechanisms involved in development of acute promyelocytic leukemia . The ...

Two-year-old Gracie McHugh was dismissed as having the flu, but her mom brought her back to the hospital after looking up her ...

Although treatment of newly diagnosed APL with anthracycline-based chemotherapy combined with ATRA has been shown to be highly effective, limiting exposure to cytotoxic chemotherapy and ...

Acute Myeloid Leukaemia (AML) with Retinoic acid receptor-gamma (RARG) fusions have similarities to Acute Promyelocytic Leukemia (APL) but are not responsive to standard APL treatments.

identifies a variant in an aggressive form of acute myelogenous leukemia (AML) known as acute promyelocytic leukemia, or APL. This variant is often missed by conventional cytogenetic techniques.

The introduction of all-trans retinoic acid in 1985 combined with anthracycline-based chemotherapy has revolutionized the prognosis of acute promyelocytic leukemia (APL) with current complete ...

The full research publication is available at: Optical Genome Mapping Reveals Complex and Cryptic Rearrangement Involving PML::RARA Fusion in Acute Promyelocytic Leukemia. Bionano is a provider of ...