For almost a century, our understanding of the tiny structure at the centre of the cell called the centrosome was limited to its ability to organize mitotic spindles and other microtubule arrays.

Taking the facts and opinions of those who have studied these bodies, into general consideration, the subject seems to be in the following condition: There is a permanent body in the cell-the ...

LM is the super-resolution technique that achieves the best spatial resolution. LM improves the lateral resolution by an order of magnitude over conventional microscopy (20-50 nm vs 250 nm). Because ...

The goal of my research is to understand the biogenesis of centrioles/centrosomes and primary cilia, and how defects in these processes affect mammalian cell physiology and evoke stress responses.

In blood cancers such as chronic lymphocytic leukemia, B cells of the immune system multiply ... A team led by the JMU biophysicist has developed a new super-resolution microscopic method.

Microtubules tend to grow out from the centrosome to the plasma membrane. In nondividing cells, microtubule networks radiate out from the centrosome to provide the basic organization of the ...

One of the proteins required for centrosome clustering is kinesin family member C1 (KIFC1/HSET), and modulation of KIFC1 stability could reduce its activity in cancer cells.

The goal of my research is to understand the biogenesis of centrioles/centrosomes and primary cilia, and how defects in these processes affect mammalian cell physiology and evoke stress responses.