The paradigm of stellate cell activation provides an important framework for defining therapeutic targets. Hepatic fibrosis is a wound healing response comprising reversible scarring that occurs ...

Studies were excluded if the wounds were stellate lacerations, puncture wounds, mammalian bites, infected, heavily contaminated or devitalized, crossing joints or mucocutaneous junctions ...

A research team has identified the transcription factor Lhx2 (LIM homeobox protein 2) as a key regulator in hepatic stellate cells. Lhx2 was found to simultaneously promote liver regeneration and ...