Together, these snRNAs and proteins form small nuclear ribonucleoprotein particles (snRNPs), setting the stage for splicing. 1 The traditional view posits that spliceosome formation is a stepwise ...

They can also be within the exon.” RBP splicing factors are sequence-specific, binding to their cognate sequence motifs like a lock and key. “Because the binding pocket of the RBP matches the sequence ...

Although scientists have determined many factors contributing to regulation of alternative pre-mRNA splicing, their current challenge is to integrate results across multiple labs and research ...

What's the difference between mRNA and pre-mRNA? It's all about splicing of introns. See how one RNA sequence can exist in nearly 40,000 different forms.