José Ignacio Jordá Llorens, Eduardo Leyva Díaz and Jessica Valdivia García, IN CSIC-UMH researchers.

Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

A comprehensive study identifies sequence features that predict tissue-specific alternative splicing. In contrast to transcription and translation, in which the flow of information from DNA to pre ...

A team of researchers has identified a mechanism that regulates the production of two different proteins from the same gene.

The discovery could pave the way for a groundbreaking RNA-based multi-cancer treatment. Alternative RNA splicing functions ...

Alternative RNA splicing is like a movie editor cutting and rearranging scenes from the same footage to create different ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns ...

Transgenic worm in which the splicing factor UNC-75, marked with the fluorophore mScarlet, reveals its expression throughout the nervous system. The worm was generated using CRISPR-Cas9 gene editing ...

Scientists reveal how cancer cells manipulate RNA splicing, increasing tumor growth. A new study introduces antisense ...

Ribopeutic Inc. has divulged nucleic acid splicing modulators (particularly, Huntingtin [HTT; HD] [mutant] and/or transcriptional activator Myb [c-Myb]) reported to be useful for the treatment of ...