One such medication is spironolactone, a water pill commonly prescribed to treat conditions like high blood pressure and heart failure that has a number of off-label uses. These include managing ...

Five patients taking spironolactone and one patient on placebo developed hyperkalemia within 2–12 weeks of initiation of study medication and were excluded. After 1 year, urinary protein ...

In a new study, de Souza and colleagues demonstrate the potent blood pressure lowering effect of low-dose spironolactone in patients with evident resistant hypertension. This finding should have ...

Spironolactone is a potassium-sparing diuretic. It is a drug most frequently used to lower blood pressure and decrease fluid retention and swelling. It is especially useful in people with liver ...