Spironolactone – sometimes called ... It’s also prescribed off acne with an initial dose is 25-50 mg/day, increasing to a maintenance dose of 50-100 mg/day. The duration of treatment ...

With spironolactone (Aldactone) treatment for acne rising several-fold in recent decades, safety concerns persist for this off-label practice in understudied populations. A database of U.S ...

In a new study, de Souza and colleagues demonstrate the potent blood pressure lowering effect of low-dose spironolactone in patients with evident resistant hypertension. This finding should have ...

investigated whether adding the aldosterone receptor antagonist spironolactone to renin–angiotensin ... they add that the initial daily dose should be ≤25 mg to reduce the risk of hyperkalemia.