The spironolactone report counted the 7,062 patients randomized to spironolactone 25 mg once daily versus placebo within 72 hours following PCI. Patients logged a median 3 years of follow-up.

However, they might recommend starting with 25 mg a day and slowly increasing your dose to reduce your risk of side effects. Spironolactone sometimes causes drowsiness, so it’s best to take it ...

Spironolactone was initiated at a dose of 25 mg daily at the first ambulatory blood pressure monitoring and titrated to 50 mg or 100 mg daily after office-based assessment of blood pressure at ...

CHICAGO -- Treatment with the potassium binder sodium zirconium cyclosilicate (SZC; Lokelma) stabilized potassium levels among patients with heart failure with reduced ejection fraction (HFrEF ...

25–50 mg daily for 1 year. Five patients taking spironolactone and one patient on placebo developed hyperkalemia within 2–12 weeks of initiation of study medication and were excluded.