Figure 1: The Sonic hedgehog (Shh ... “No one to this day understands specifically how aberrant hedgehog pathway activation causes cell transformation.” Hedgehog-associated genetic mutations ...

Chickens treated to inhibit the sonic hedgehog (Shh) pathway during development grow feathers that resemble ancient ...

In a study published in PLOS Biology, researchers blocked a developmental pathway called “sonic hedgehog” (named after the video game character) in chicken embryos. This caused the chickens to ...

Alteration of the expression of the co-called 'Sonic Hedgehog' gene can transform feet scale and wing feathers. While a transient over-expression of the gene can permanently turn feet scales into ...