Smallpox, one of the biggest killers in history, is caused by a virus called variola. Variola causes a distinctive rash and is often lethal. The name variola comes from the Latin word for “spotted” ...

the vaccinia virus (VACV), was used in the past as a live vaccine to eradicate smallpox. Despite intensive research, important questions regarding the biogenesis and structure of the mature virus ...

Learn about our Editorial Policies. Thanks to a Cold War-era division of responsibility, smallpox has been held in just two places in the world since 1984: at the CDC labs in Atlanta, and at Vector, a ...

2004). The human influenza virus genome, by contrast, encodes only 11 proteins; and the smallpox genome encodes fewer than 200 proteins. To further analyze this large virus, investigators next ...

Today there is mounting concern about the threat of a bioterrorist attack using smallpox—so much concern ... body against some kind of pathogen—a virus or bacteria or some other agent that ...