Sitagliptin (Januvia™) is a new oral agent ... GLP-1 exerts other significant actions to modulate intermediary metabolism, including stimulation of insulin biosynthesis, slowing gastric emptying ...

Researchers from the US have shown that combination therapy with sitagliptin and metformin results in a substantial and additive glycemic improvement in patients with type 2 diabetes. Sitagliptin ...

Expert Rev Endocrinol Metab. 2008;3(6):691-697. Elimination of sitagliptin occurs primarily via renal excretion (79%) and involves active tubular secretion. Sitagliptin is a substrate for human ...