to achieve plasma concentrations of sitagliptin similar to those in patients with normal renal function, a dosage adjustment is recommended for patients with moderate renal insufficiency (50 mg ...
Previously on Janumet: maintain same total daily dose of each component. All: max 100mg sitagliptin/2000mg metformin per day. Renal impairment (eGFR 30–45mL/min/1.73m 2): initiation not ...
A total of 1,091 patients with type 2 diabetes and HbA 1c levels of 7.5–11.0% were randomly assigned to receive combination therapy with daily sitagliptin (100 mg) and metformin (either 1,000 mg ...
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