Here we report the application of high-density oligonucleotide array (DNA chip)-based analysis to determine the distant history of single nucleotide polymorphisms (SNPs) in current human populations.

Because single-nucleotide mutations in a DNA sequence can have unpredictable effects on its function, the PTO is less likely to allow broad claims to ESTs and SNPs absent a specification that ...

Imagine creating a comprehensive, searchable index for a library containing hundreds of millions of books—a task that would ...

DNA is fundamental to the biology of all life on Earth, but how many of us actually know what it is or what it's made of?

Imagine creating a comprehensive, searchable index for a library containing hundreds of millions of books - a task that would ...

The new review, detailed in the journal Frontiers in Psychology, examines over a dozen genetic studies published in the past ...

It involves using a long single-stranded DNA (ssDNA) that is folded into designated shapes with the help of hundreds of short DNA staple strands. This technique allowed for the creation of larger DNA ...

This allows researchers to sequence all four DNA bases and distinguish between 5mC and 5hmC. Using the data analysis package, researchers obtain a single multiomic dataset from which they can assess ...

Rapid nucleotide sequence changes in mtDNA lead to accumulated differences that ... an advanced tissue processing system that streamlines critical sample preparation steps for single cell sequencing, ...

For DNA to replicate, the helix must first unwind and break the DNA from a double strand into two single strands. Credit: Taha Shahid et al Upon binding, helicases melt the DNA, breaking the ...