Senescent cells have both harmful roles ... characterized by increased Senescence-Associated β-Galactosidase (SA-β-Gal) staining and reduced Ki67 expression. Additionally, p16-tdT cells ...

After treating a tumor with chemotherapy and radiotherapy, cells known as senescent cells can appear. These are cells that do not divide, are involved in the aging process and are resistant to ...

Functional subpopulations of β-cells emerge to control pulsative insulin secretion in the pancreatic islets of mice through calcium oscillations.

The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological significance have been reviewed.

Studying how and why these spurious transcripts are produced in senescent cells as well as their impact on the cell itself could hold important implications for aging and longevity ...

The little black mouse’s feet dangled above the table as the animal clutched a horizontal wire with its two front paws. After just a few seconds, it lost its grip and fell onto a pile of bedding below ...

Traditional methods for detecting senescent cells, such as β-galactosidase staining and immunohistochemistry, have limitations in terms of specificity and sensitivity. The introduction of ...

In the course of their study, the researchers found that diseases associated with aging and obesity are triggered and progress when senescent cells accumulate in internal organs, blood vessels and ...

Yang Y, Jn-Simon N, He Y, Sun C, Zhang P, Hu W, Tian T, Zeng H, Basha S, Huerta AS, Sun LZ, Yin XM, Hromas R, Zheng G, Pi L, ...

After treating a tumour with chemotherapy and radiotherapy, cells known as senescent cells can appear. These are cells that do not divide, are involved in the ageing process and are resistant to cell ...