These results highlight SOX9 as a promising therapeutic target for treating MASH. The transcription factor sex-determining region Y-related high-mobility group-box gene 9 (SOX9) plays a critical ...

The transcription factor sex-determining region Y-related high-mobility group-box gene 9 (SOX9 ... inhibitor to test whether SOX9 acts via AMPK activation. SOX9 expression was significantly ...

“At Day 10, some cells’ descendants were fully healed while others were not. The cell lineage that healed had switched off SOX9 expression, while the unhealed lineage, in a continuing attempt to fully ...