In the case of the trp operon, the ligand tryptophan is required for the repressor to work (repressible negative regulation). But other operons respond to the presence of their small molecule ...
An international collaboration has achieved an important breakthrough in understanding the genetic mechanisms that allow bacteria to build resistance to drugs. Bacteria have multiple defense ...
The operon is regulated by Lac repressor, the product of the lacI gene, which is transcribed from its own promoter (PI). The repressor inhibits transcription by binding to the lac operator (O).