Forensic science has always relied heavily on the power of DNA to solve crimes, establish identities, and uncover hidden ...

Most cells in the human body each contain about six feet of DNA. Yet the nucleus, where DNA is coiled, is no larger than a ...

Each gene has a regulatory region that contains instructions on when and where the gene is expressed. This information is written in a code that is read by transcription factors, which bind to ...

In immune cells, for example, 30% of the enhancers (a specific type of regulatory DNA element) are derived from ERVs.” Matteo ...

The way DNA folds inside the nucleus of brain cells may hold the key to understanding a devastating form of brain cancer ...

Next-generation DNA sequencing (NGS) has transformed the way scientists understand genetics. With the ability to sequence DNA ...

Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal cellular functions. The ...

Extrachromosomal DNAs (ecDNAs) encode oncogenic driver proteins, regulatory elements, immunomodulators, and genes of yet-unknown oncogenicity (Panel A). They exist as circular pieces of DNA in the ...

Guanine-rich sequences in DNA can form unique secondary structures, such as G-quadruplexes, which are involved in the regulation of gene expression. These structures can influence the binding of ...