Although segmental rearrangement of an undefined receptor may have greatly increased the recognition potential for antigen, a mechanism to further amplify the repertoire by selectively increasing ...

Amongst the latter, TCRα rearrangements were not identified ... demonstrate no ectopic TLX1/3 expression and the molecular mechanisms responsible for the maturation arrest remain unknown.

A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled “Acquired RUFY1-RET rearrangement as a ...

Wu, J. L., & Iams, W. T. (2025). Acquired RUFY1-RET rearrangement as a mechanism of resistance to lorlatinib in a patient with CD74-ROS1 rearranged non-small cell lung cancer: A case report ...

In most cases of B-ALL with MLL rearrangements (MLLr B-ALL), this ... The activation of FLT3 promotes the proliferation mechanisms of the cell, a hallmark of cancer, one of which is the ...