We achieved activation of pathways downstream of Ras by infecting tv-a + cells with ... 45 min and pelleting of debris by centrifugation. Protein samples (40 μg) were separated by 10% SDS ...

Ras proteins are synthesized in the cytosol as soluble precursors that are modified by the permanent addition of a farnesyl isoprenoid (F) to the C terminus of the protein. Following farnesylation ...

VVD-159642, Vividion's fourth clinical-stage program stemming from its chemoproteomics discovery platform, is designed to improve patient outcomes by inhibiting RAS-PI3Ka, a key signaling pathway ...

The CD1 gene family in mammals is responsible for protein synthesis that protects ... (Kaliningrad), the Institute For Molecular Biology RAS (Moscow), Institute of Molecular Cell Biology SB ...