What's the difference between mRNA and pre-mRNA? It's all about splicing of introns. See how one RNA sequence can exist in nearly 40,000 different forms. Next, the snRNPs U2 and U4/U6 appear to ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...

The realization that most human genes generate multiple mRNAs encoding divergent protein isoforms via alternative splicing and polyadenylation has revealed extensive regulation that remains to be ...

DExH/D box proteins are required for the major transactions of RNA, including mRNA synthesis, pre-mRNA splicing ... The NPH-II model of RNPase activity establishes proof-of-principle, but it ...

Cambridge, Massachusetts-based Envisagenics focuses on using AI to analyse errors in RNA splicing, a process in which a precursor form of messenger RNA (mRNA) – which is used as a template for ...

They can also be within the exon.” RBP splicing factors are sequence-specific, binding to their cognate sequence motifs like a lock and key. “Because the binding pocket of the RBP matches the sequence ...

"By targeting key processes like RNA splicing and modification ... from my lab and merge them with Leslie's powerful and robust model systems to nail down this novel mechanism," said co ...

By targeting key processes like RNA splicing and modification ... from my lab and merge them with Leslie's powerful and robust model systems to nail down this novel mechanism." ...

"By targeting key processes like RNA splicing and modification ... from my lab and merge them with Leslie's powerful and robust model systems to nail down this novel mechanism," said co ...

In myotonic dystrophic patients, titration of MBNL protein by RNA containing expanded CUG repeats leads to expression of a fetal splicing form of the cardiac sodium channel, SCN5A, inappropriate ...

In this webinar, Dr. Megan L Noonan will present her research on the role of alternative splicing in kidney disease progression, discussing how she used nanopore RNA sequencing to accurately detect ...