RNA levels of the remaining 5,000–6,000 standard yeast genes vary over a wide range, but together represent ∼ 50% of all Pol II transcription 13, which gives an average value for a standard ...

Like Mediator and TFIID, TFIIH is required for pol II transcription, genome-wide ... The Mediator complex as a master regulator of transcription by RNA polymerase II. Nat Rev Mol Cell Biol 2022, 23: ...

mRNA transcription by RNA polymerase II (Pol II) is rapidly regulated in response to many different types of cellular stress, including heat shock. In response to heat shock in human cells, several ...

在这里，作者报道了核ANLN通过与RNA Pol II相互作用并促进其聚类和相分离在基因转录 ... 的研究人员在Nature Communications期刊上发表了题为 “Nuclear ANLN regulates transcription initiation related Pol II clustering and target gene expression” ...

In Eukarya, RNA Polymerase II (Pol II) transcription is a highly regulated process, which is responsible for the transcription of all protein encoding genes. While the catalytic core of the Pol II ...

2025年1月29日，中国科学院微生物研究所 邓涛研究员与高福院士团队合作在Nucleic Acids Research在线发表了题为Influenza A virus NS2 protein acts on vRNA-resident ...

Anillin (ANLN), a mitotic protein that regulates contractile ring assembly, has been reported as an oncoprotein. However, the function of ANLN in cancer cells, especially in the nucleus, has not been ...

Our mission is to elucidate fundamental mechanisms that control the elongation phase of transcription by RNA polymerase II (Pol II) in normal and disease states. We are particularly interested in ...