Crucially, the approach works even with the predicted structures of proteins that have never been experimentally determined. It has implications for the massive amount of structural data being ...

Proteins, the pillars of cellular function, often assemble into 'complexes' to fulfill their functions. A study reveals why this assembly often begins during the very process of protein synthesis or ...

Introduction Definition of Peptides Peptides are short chains of amino acids linked by peptide bonds, typically consisting of 2 to ...

Low-density lipoproteins (LDL) - commonly known as bad cholesterol - have long been on scientists' radar as a major contributor to heart disease.

Simplified redesign of proteins to improve ligand binding Date: January 21, 2025 Source: University of Alabama at Birmingham Summary: The ability to alter proteins to refine control over binding ...

The formation of protein complexes is a delicate process, with some proteins finding their match at synthesis.

It has been a few years since AI began successfully tackling the challenge of predicting the three-dimensional structure of proteins, complex molecules that are essential for all life. Next ...

Crucially, the approach works even with the predicted structures of proteins that have never been experimentally determined. It has implications for the massive amount of structural data being ...

Biomedical engineers at Duke University have developed an AI-based platform that designs short proteins, termed peptides, capable of binding and destroying previously undruggable disease-causing ...

A study in the journal Pharmaceuticals has uncovered how specific genetic mutations in α2δ-1 and α2δ-3 proteins linked to ...