epidermal growth factor receptor, SRC kinase, SHC kinase, protein kinase C (PKC), adenylyl cyclase and GTP proteins (for details, see the Signal Transduction Knowledge Environment website under ...

Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase first identified ... In cancers, all translocations involving ALK produce fusion proteins with constitutive tyrosine kinase activity ...

Dr. Xiaohu Zhang, co-founder and CEO of Accropeutics said, "Dosing of the first patient in AC-101's Phase 1b study represents a significant step towards advancing this novel oral therapeutic for ...

Announcing a new article publication for BIO Integration journal.   Diabetes, a common metabolic condition, poses a substantial health burden worldwide. To revolutionize diabetes management, enhance ...

It is closely associated with tumorigenesis and drug resistance, making it a potential target for oncology drug development. To date, no ROR1-targeting drugs have been marketed. BR111 utilizes ...