epidermal growth factor receptor, SRC kinase, SHC kinase, protein kinase C (PKC), adenylyl cyclase and GTP proteins (for details, see the Signal Transduction Knowledge Environment website under ...
Dr. Xiaohu Zhang, co-founder and CEO of Accropeutics said, "Dosing of the first patient in AC-101's Phase 1b study represents a significant step towards advancing this novel oral therapeutic for ...
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase first identified ... In cancers, all translocations involving ALK produce fusion proteins with constitutive tyrosine kinase activity ...
Announcing a new article publication for BIO Integration journal.   Diabetes, a common metabolic condition, poses a substantial health burden worldwide. To revolutionize diabetes management, enhance ...
Adrenomedullin (ADM) inhibits endothelial insulin signaling, contributing to obesity-associated insulin resistance, according ...
It is closely associated with tumorigenesis and drug resistance, making it a potential target for oncology drug development. To date, no ROR1-targeting drugs have been marketed. BR111 utilizes ...