By employing a novel technique to examine how carbohydrates modify proteins, scientists have found that gut bacteria can ...

The glycosylation of proteins to create glycoproteins is very common and has been linked to changes in cell adhesion, cell signaling, protein folding and receptor activation processes ...

Glycan composition is a critical quality attribute that affects the stability, safety and efficacy of protein therapeutics. As glycosylation profiling requirements evolve across drug development ...

A new study reveals that gut bacteria influence brain protein modifications via glycosylation. Researchers identified over ...

Lasker Foundation Website (2009). Ungar, D. Golgi linked protein glycosylation and associated diseases. Seminars in Cell and Developmental Biology 20, 762–769 (2009). Xu, D. & Esko, J.

Glycosylation can help a protein achieve folding and can facilitate signalling and cell–cell adhesion. Here the authors present deep quantitative glycoprofiling (DQGlyco), a method that enables ...

Sialic acids are a family of alpha-keto acid sugars with a nine-carbon backbone, functioning as terminal sugars on cell surface glycoproteins and glycan receptors for cellular recognition.

“Palleon’s glycan editing therapeutic has the potential to significantly improve treatment outcomes in patients who have autoimmune diseases including lupus nephritis, with a therapy that ...

Every cell in the human body is covered by a layer of sugar molecules, also called glycans, which are involved in processes that are essential for life. Glycan molecules come in different shapes and ...