The amino acid sequence of a protein encodes its three-dimensional structure and determines its ... is a known suppressor of missense mutations 12, and crystal structures suggest that the mutant ...

Information derived from the crystal structures of the periplasmic protein FhuD ... In this study, we describe the 1.9 Å resolution structure of E. coli FhuD in complex with gallichrome.

For years, the standard way to study protein structure was to form a crystal and study the way that crystal diffracts X-rays. However, some proteins are difficult or even impossible to crystalize.

Players of an online game that allows users to adjust how proteins are folded have solved a decade-long protein structure mystery. Jef Akst was managing editor of The Scientist, where she started as ...

View Full Profile. Learn about our Editorial Policies. While AlphaFold and the subsequent AI revolution in biology garnered a lot of attention, the foundational bricks for the strides made in protein ...

Many leading drugs today are the product of structure-based drug design. While enormous strides have been made in the last decade, there remain a large number of important proteins where the ...

Our project focuses on analyzing how proteins assemble on membranes using Atomic Force Microscopy. With high-resolution, fast-scan Atomic Force Microscopy, we will directly visualize the structure and ...

Ribosomal functions beyond protein synthesis have been uncovered ... with the ribosomal tunnel and rearrange the internal structure, resulting in elongation stalling—known as "translation ...