The path of primordial germ cells illustrates the complexities of imprinted DNA, which contains epigenetic marks that turn on and off when necessary. Differences between the maternal and paternal ...

Understanding how cells transform into specialized types during human development is a central challenge in biology. This ...

In the intricate science of reproduction, the creation of offspring has long relied on the union of sperm and eggs, whether ...

The germ cell lineage ensures the creation of new individuals, diversifying the genetic and epigenetic information. We have succeeded in inducing mouse embryonic stem cells (mESCs)/induced pluripotent ...

Two weeks after a human egg is fertilized, primordial germ cells (PGCs), which develop into sperm and eggs, are formed. In six to 10 weeks after fertilization, PGCs differentiate into pro ...