This highlights the importance of drug combinations in achieving ... focus has been on the use of premedication to enhance the safety and efficacy of anesthesia. A study involving C57BL/6J mice ...

Premedication: 50–100mcg (1–2mL) by IM inj 30–60 mins prior to surgery. Adjunct to general anesthesia (low dose ... Bradyarrhythmias. Drug abusers. Renal or hepatic impairment.

A total of 122 adults (mean age, 57.4 years; 63.9% women) awaiting elective surgery under general anesthesia were included ... and the need for anxiolytic premedication. The lack of an active ...