A severe form of this allergy is the Systemic nickel allergy syndrome, clinically characterized by cutaneous manifestions (contact dermatitis, pompholyx, hand dermatitis dyshydrosis, urticaria ...

Many clinicians use the terms "chronic vesicular hand dermatitis," "dyshidrotic eczema," and "pompholyx" interchangeably. We use the terms used by Warshaw and colleagues. [18] They described ...