Thioredoxin, which is ubiquitous in cells, binds to TBD, triggering a conformational change that helps TBD enhance the polymerase’s processivity. “So, it was along the same lines as thinking about if ...

View Full Profile. Learn about our Editorial Policies. Polymerase chain reaction (PCR) is a fundamental molecular biology tool that scientists use to amplify and analyze genetic material, such as DNA ...

If processivity and fidelity are indeed unaffected ... The Pacific Biosciences system can also measure enzyme kinetics of single polymerase molecules. The authors presented data revealing that ...

Gene expression is linked to RNA transcription, which cannot happen without RNA polymerase. However, this is where the similarities between prokaryote and eukaryote expression end. Central to the ...

The role of XPB/Ssl2 dsDNA translocation processivity in transcription start-site scanning ... DJ. TFIID enables RNA polymerase II promoter-proximal pausing. Mol Cell 2020, 78: 785 – 793. Schier, AC; ...

The role of XPB/Ssl2 dsDNA translocation processivity in transcription start-site scanning ... Taatjes, DJ. TFIID enables RNA polymerase II promoter-proximal pausing. Mol Cell 2020, 78: 785 – 793.