If processivity and fidelity are indeed unaffected ... The Pacific Biosciences system can also measure enzyme kinetics of single polymerase molecules. The authors presented data revealing that ...

Thioredoxin, which is ubiquitous in cells, binds to TBD, triggering a conformational change that helps TBD enhance the polymerase’s processivity. “So, it was along the same lines as thinking about if ...

An unprecedented DNA polymerase V transactivation mechanism, which involves the RecA protein, sheds new light on unresolved issues that have persisted over time, prompting us to reflect on ...