IPA: Inhibition of platelet aggregation ... The combined use of antiplatelet drugs acting through different mechanisms is important in antithrombotic treatment of patients with cardiovascular ...

P2Y12 inhibitors such as Plavix (clopidogrel ... whereas antiplatelets prevent platelets from clumping together. These medications share some side effects, such as an increased risk of bleeding ...

All COX2 inhibitors undergo oxidative drug metabolism by cytochrome P450 ... 50 is not only a potent inhibitor of platelet aggregation, but also interferes with processes leading to hypertension ...

resulting in low potential drug–drug interactions. When given as an intravenous bolus, immediate and full platelet inhibition of ADP-induced platelet aggregation was observed. The clinical ...