In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive antibiotic resistance and even shape entire ecosystems. Now an interdisciplinary ...

A plasmid is a small, circular, double-stranded DNA molecule that is distinct from a cell's chromosomal DNA. Plasmids naturally exist in bacterial cells, and they also occur in some eukaryotes.

High-resolution in vivo imaging of gene expression is not possible in opaque ... injected with 4–16 nl of 20 ng μl −1 linearized plasmid rather than mRNA. This yields ∼88–352 copies ...

The ability to control gene expression across a wide range is crucial for many fields, including bioengineering, disease detection, and environmental monitoring. Research led by Lingchong You, Ph ...

The GENE PREP has protocols for DNA purification and extraction from tissues, cells, plants and plasmid preps.

Commonly used gene-editing systems such as CRISPR rely ... and outperformed a widely used DNA plasmid-based delivery system. It improved average editing efficiency by 4.3 times when used for ...

Axovia’s lead program is a AAV9-based gene therapy targeted at treating retinal dystrophy associated with BBS. Charles River's HQ plasmid DNA production will support Phase 1 studies for the BBS ...

Building a gene editor took months. With CRISPR even high-schoolers can get hold of editing systems in the time it takes to order RNA sequences online and have them shipped by FedEx. In a short ...

The Gene Vector Core was awarded the Blue Flame Award. The award is given to scientists who have at least one plasmid deposited that has been distributed at least 100 times. The Gene Vector Core was ...