A scaleable method for the liquid-phase separation of plasmid DNA from RNA. In the course of experiments on the potential of nucleic acid compaction for enhancement of chromatographic adsorption ...

Scientists in The Wistar Institute lab of David B. Weiner, Ph.D., have described a next-generation vaccination technology ...

Initially, the agrobacterium cell contains a bacterial chromosome and a Tumor-inducing plasmid (Ti plasmid). The Ti plasmid is removed from the agrobacterium cell, and a restriction enzyme cleaves the ...

“I then purified this plasmid cloning vector that had the gal operon and showed that I could ... Therefore, Mertz began a side project looking at the infectivity of different forms of the viral DNA.

Credit: Beckwith et al., Cell. From their data, the scientists realized that during cell division, DNA forms loops in two stages. First, it forms stable large loops, which then subdivide into ...