A new study reports that mirodenafil, a newly developed oral phosphodiesterase type 5 (PDE5) inhibitor, is an efficacious and safe treatment for erectile dysfunction (ED). Many men with ED ...

The introduction of inhibitors of the cyclic GMP phosphodiesterase (PDE) 5 into clinical urology is mainly the result of the characterization of the physiology of nonvascular and vascular penile ...

For many couples sexual activity is unplanned, so phosphodiesterase type 5 inhibitor therapy that allows a wide time-frame for achieving successful intercourse would give couples more freedom to ...

The dose of phosphodiesterase type-5 inhibitors varies depending upon what is being treated. The 2022 US study included men and women with pulmonary hypertension only. The UK study only had men ...

Researchers were originally studying sildenafil as a potential treatment for high blood pressure. However, during clinical ...

(Spoiler: It is.) While generic sildenafil and Viagra are equally safe and effective phosphodiesterase type 5 (PDE5) inhibitors, they have one key difference: price. Viagra costs $90 to $139 per ...

Objective: Given the therapeutic and non-therapeutic use of the tadalafil, (phosphodiesterase-5 inhibitor, PDE-5i), we examined its effects on anaerobic performance indices. Methods: In total, 12 well ...