Promethazine concentration was determined by high-performance liquid chromatography, and pharmacokinetic values were calculated with noncompartmental methods. This study compared the ...

The optimization of pharmacokinetic properties is crucial in the design of successful drug candidates. Tune in as Punit Marathe shares the key pharmacokinetic concepts including clearance, volume of ...

Purpose Pharmacokinetic considerations in patients who have undergone Roux-en-Y gastric bypass (RYGB) are explored. Summary The prevalence of obesity, especially morbid obesity, has dramatically ...

Preclinical pharmacokinetic studies can determine the optimal dose for administration, time taken to achieve steady state, and dosage intervals. The DMPK services that we offer include: Drug and ...

Pfizer on Monday announced it is halting development of a daily weight loss pill after one patient experienced a liver injury ...

Assessing the pharmacokinetics (PK) of antibody-drug conjugates (ADCs) in both preclinical and clinical settings is crucial for their development. Biotransformation processes can lead to the ...

Data supports the novel Trans-Arterial Micro-Perfusion (TAMP TM) therapy platform for targeted chemotherapy delivery for the potential to minimize a therapy’s toxicities versus systemic ...

CsA Ophthalmic Gel is an innovative cyclosporine gel being developed by Zhaoke in China for the treatment of moderate to ...

Earlier this month, the company released a new version of the Simcyp Simulator for physiologically-based pharmacokinetic (PBPK) modeling, which forecasts the behavior of drugs in different body ...