This strategy can help determine what dose should be further tested. Abbreviations: PD, pharmacodynamic; PK, pharmacokinetic. There are several applications of PK/PD modeling in clinical development.

The improvement of our understanding on the pharmacokinetic and pharmacodynamic characteristics of these drugs enables the tailoring of the most appropriate anti-thrombotic therapy to the ...

These patients continue to receive TTX-MC138 in cycles of approximately 28 days. PK and pharmacodynamic (PD) analyses from Cohorts 1 and 2 are ongoing, with results so far indicating that TTX ...

We expect successful applicants to demonstrate: Interest and basic understanding of pharmacokinetics and pharmacodynamic concepts. Numerical ability. Prior experience and/or evidenced interest in use ...

Expert Rev Clin Pharmacol. 2012;5(3):319-336. Finally, a recent study suggested that although prasugrel significantly reduces thrombotic events in patients with ACS undergoing PCI because of its ...